Gleaning Insights for Stem Cell Therapy in Treating Respiratory Diseas…
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작성자 Sven 댓글 0건 조회 11회 작성일 24-09-07 12:15본문
The use of stem cells in the treatment of lung diseases has a ton of potential. We expect to be able to go forward with additional evaluation of stem cells or regeneration medicine and other cell treatments in lung disorders as we understand further their therapeutic properties.
India is the fastest-growing economy in the world and the whole credit goes to revolutionary industrialization. But as per the saying "something good always seems to come from something bad" is true for anthropogenic pollution which is helping India to top the charts of most polluted countries in the world. With pollutions comes health risks especially respiratory illness. Respiratory diseases are the most common cause of morbidity and mortality in the world. As per the GBD (Global Burden of Disease) reports, about one-fourth of deaths worldwide due to respiratory illness occur in India. Chronic Obstructive Pulmonary Disease (COPD), Tuberculosis, Asthma, Pneumonia, Allergy, Emphysema, Cystic Fibrosis (CF), and Lung cancer are the most common respiratory illnesses killing millions per year.
Factors fuelling respiratory diseases
COPD is a common cause of mortality globally; affecting 251 million people and killing approximately 3.15 million people per year. COPD is considered to be the second biggest cause of death in India. There are secondary causes of respiratory illness also, like occupational risks (for e.g. emphysema in construction workers), chronic diseases affecting respiratory muscles (e.g. Amyotrophic lateral sclerosis ) seasonal allergies like asthma and pollution-related bronchitis, etc. patients suffering from chronic diseases like ALS are usually succumbed to respiratory failure due to muscle stiffness and difficulty in breathing.
Likewise, patients with cystic fibrosis develop respiratory illness, and the management of such patients becomes very difficult. Some worst scenarios require putting the patient on ventilation, which further increases the chances of becoming infected or acquiring hospital-associated pneumonia. Respiratory problems also add to an increased hospital stay, ventilator days, cost of treatment with almost less or no chances of easy recovery. The economic burden of respiratory disease is not different from any other calamity.
As per a study published in Lung India, the mean annual cost per patient was found to be US$637, which is increasing rapidly. Conventional treatments for respiratory illness usually include drugs, pumps, mechanical ventilation which are not only costly but put the patients at other health risks. In lower-income countries, treatment options are limited and restricted to medications only which do not assure recovery of the sufferers, and chances of relapses are usually very high due to poor medication adherence.
Regenerative Medicine: A boon?
Scientists and researchers across the globe are working continuously to find a cure for such diseases with no or lesser health risks and cost-effectiveness. Regenerative medicine or stem cell treatments cell therapy has proved to be a boon for both researchers and sufferers due to its embarking effectiveness against respiratory as well as associated chronic illnesses like ALS and Cystic Fibrosis.
A new study on Mesenchymal Stem Cell therapy has shown positive results in the treatment of COPD and CF. Most of the patients are now relying on stem cell therapy over conventional treatments due to less relapse rate and easy recovery. There are many respiratory diseases that require transplantation and are thought to be caused by adult stem cells dysfunctioning for e.g. Idiopathic Pulmonary Fibrosis (IPF) is another major cause of morbidity and usually requires transplantation which is very costly and does not ensure complete cure. With age, the cell loses their longevity and stem cells are generally exhausted thus, most elderly are affected with respiratory illnesses but some chronic conditions like COPD, CF, ALS, MND, and IPF cause premature aging of stem cells, to rescue such patients stem cell treatments cells therapy comes handy.
The Upshot
Stem cells therapy has the ability to repair inflamed cells and tissue and thus rejuvenate normal cell functioning. Lungs are lined by mesenchymal cells which are usually inflamed in respiratory diseases. To cure this inflammation, mesenchymal stem cell therapy or MSC therapy has proven to be best to date. It holds a greater potential for the treatment of many such diseases, which is a limitation of many conventional treatments. However, being a developing country, there are very few treatment centers available in India. Regenerative medicine being a newer technology requires skilled and knowledgeable staff, which poses a great difficulty in front of patients because of limited choice available. It is always important to get treated from a cGMP laboratory. GMP certification ensures that the cells for therapy being tested and developed in vitro are done safely and under the highest standards and quality control.
Advancells is a Noida-based stem cell research-based company and is one such lab that ensures all quality checks and maintains good lab practices so that they can deliver the best to their patients. Being at forefront of regenerative medicine in India, We are continuously proving ourselves in technology transfer and as lead stem cell therapy providers. Our aim is to provide a highly customized treatment protocol for each patient, they ensure the best for our patients.
India is the fastest-growing economy in the world and the whole credit goes to revolutionary industrialization. But as per the saying "something good always seems to come from something bad" is true for anthropogenic pollution which is helping India to top the charts of most polluted countries in the world. With pollutions comes health risks especially respiratory illness. Respiratory diseases are the most common cause of morbidity and mortality in the world. As per the GBD (Global Burden of Disease) reports, about one-fourth of deaths worldwide due to respiratory illness occur in India. Chronic Obstructive Pulmonary Disease (COPD), Tuberculosis, Asthma, Pneumonia, Allergy, Emphysema, Cystic Fibrosis (CF), and Lung cancer are the most common respiratory illnesses killing millions per year.
Factors fuelling respiratory diseases
COPD is a common cause of mortality globally; affecting 251 million people and killing approximately 3.15 million people per year. COPD is considered to be the second biggest cause of death in India. There are secondary causes of respiratory illness also, like occupational risks (for e.g. emphysema in construction workers), chronic diseases affecting respiratory muscles (e.g. Amyotrophic lateral sclerosis ) seasonal allergies like asthma and pollution-related bronchitis, etc. patients suffering from chronic diseases like ALS are usually succumbed to respiratory failure due to muscle stiffness and difficulty in breathing.
Likewise, patients with cystic fibrosis develop respiratory illness, and the management of such patients becomes very difficult. Some worst scenarios require putting the patient on ventilation, which further increases the chances of becoming infected or acquiring hospital-associated pneumonia. Respiratory problems also add to an increased hospital stay, ventilator days, cost of treatment with almost less or no chances of easy recovery. The economic burden of respiratory disease is not different from any other calamity.
As per a study published in Lung India, the mean annual cost per patient was found to be US$637, which is increasing rapidly. Conventional treatments for respiratory illness usually include drugs, pumps, mechanical ventilation which are not only costly but put the patients at other health risks. In lower-income countries, treatment options are limited and restricted to medications only which do not assure recovery of the sufferers, and chances of relapses are usually very high due to poor medication adherence.
Regenerative Medicine: A boon?
Scientists and researchers across the globe are working continuously to find a cure for such diseases with no or lesser health risks and cost-effectiveness. Regenerative medicine or stem cell treatments cell therapy has proved to be a boon for both researchers and sufferers due to its embarking effectiveness against respiratory as well as associated chronic illnesses like ALS and Cystic Fibrosis.
A new study on Mesenchymal Stem Cell therapy has shown positive results in the treatment of COPD and CF. Most of the patients are now relying on stem cell therapy over conventional treatments due to less relapse rate and easy recovery. There are many respiratory diseases that require transplantation and are thought to be caused by adult stem cells dysfunctioning for e.g. Idiopathic Pulmonary Fibrosis (IPF) is another major cause of morbidity and usually requires transplantation which is very costly and does not ensure complete cure. With age, the cell loses their longevity and stem cells are generally exhausted thus, most elderly are affected with respiratory illnesses but some chronic conditions like COPD, CF, ALS, MND, and IPF cause premature aging of stem cells, to rescue such patients stem cell treatments cells therapy comes handy.
The Upshot
Stem cells therapy has the ability to repair inflamed cells and tissue and thus rejuvenate normal cell functioning. Lungs are lined by mesenchymal cells which are usually inflamed in respiratory diseases. To cure this inflammation, mesenchymal stem cell therapy or MSC therapy has proven to be best to date. It holds a greater potential for the treatment of many such diseases, which is a limitation of many conventional treatments. However, being a developing country, there are very few treatment centers available in India. Regenerative medicine being a newer technology requires skilled and knowledgeable staff, which poses a great difficulty in front of patients because of limited choice available. It is always important to get treated from a cGMP laboratory. GMP certification ensures that the cells for therapy being tested and developed in vitro are done safely and under the highest standards and quality control.
Advancells is a Noida-based stem cell research-based company and is one such lab that ensures all quality checks and maintains good lab practices so that they can deliver the best to their patients. Being at forefront of regenerative medicine in India, We are continuously proving ourselves in technology transfer and as lead stem cell therapy providers. Our aim is to provide a highly customized treatment protocol for each patient, they ensure the best for our patients.
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